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Transduction Mechanisms in Cellular Signaling: Cell Signaling Collection
출판사 : Academic Press
저 자 : Dennis
ISBN : 9780123838629
발행일 : 2011-4
도서종류 : 외국도서
발행언어 : 영어
페이지수 : 610
판매가격 : 59,000원
판매여부 : 재고확인요망
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   Transduction Mechanisms in Cellular Signaling: Cell Signaling Collection 목차
Section A - Overview
1. Intracelluar Signaling

Section B - Phosphorylation/Dephosphorylation

Part 1 Kinases
2. Eukaryotic Kinomes: Genomics and Evolution of Protein Kinases
3. Modular Protein Interaction Domains in Cellular Communication
4. Recognition of Phospho-Serine/Threonine Phosphorylated Proteins by phospho-Serine/
Theonine-Binding Domains
5. Protein Kinases Inhibitors
6. Principles of Kinase Regulation
7. Mammalian MAP Kinases
8. The Negative Regulation of JAK/STAT Signaling
9. Protein Porximity Interactions
10. Global Analysis of Phosphoregulatory Networks

Part 2 Phosphatases
11. Phosphatase Families Dephosphorylating Serine and Threonine Residues in Proteins
12. The Structure and Topology of Protein Serine/ Threonine Phosphatases
13. SH2 Domain-Containing Protein-Tyrosine Phosphatases
14. Calcineurin
15. Protein Seine/ Threonine-Phosphatase 2C(PP2C)
16. Inhibitors of Protein Tyrosine Phosphatases
17. MAP Kinase phosphatases
18. Protein Phosphatase 2A

Section C - Lipid Signaling

19. Lipid-Mediated Localization of Signaling proteins
20. Structural Principles of Lipid Second Messenger Recognition
21. Pleckstrin Homology(PH)
22. PX Domains
23. FYVE Domains in Membrane Trafficking and Cell Signaling
24. Type I Phosphatidylinositol 4-Phosphate5-Kinases(PHP 5-Kinases)
25. Phosphoinositide 3-Kinases
26. Inositol Pentakisphosphate: A Signal Transduction Hub
27. IP3 Receptors
28. PTEN
29. PTEN/MTM Phosphatidylinositol Phosphatases
30. Diacylglycerol Kinases
31. Phospholipase
32. Phospholipase D
33. Role of Phospholipase A2 Forms in Arachidonic Acid Mobilization and Eicosanoid Generation
34. Prostaglandin Mediators
35. Leukotriene Mediators

Section D - Cyclic Nucleotides

36. Sphingosine-1-Phosphate REceptors: An Update
37. Adenylyl Cyclases
38 Phosphodiesterase Families
39. cAMP- Dependent Proetin Kinase
40. Cyclic GMP-Dependent Protein Kinase: Targeting and Control of Expression
41. Substrates of Cyclic Nucleotide-Dependent Protein Kinases
42. Physiological Substrates of PKA and PKG
43. Ingibitors of Cyclic AMP-and Cyclic GMP-Dependent Protein Kinases
44. AKAP Transduction Units: Context dependent Assembly of Signaling Complexes
45. Cyclic Nucleotide Specificiy and Cross - Activation of Cyclic Nucleotide Receptors

Section E - G-Proteins
46. Signal Transduction by G Proteins: Basic Principles, Molecular Diversity,
and Structural Basis of Their, Actions
47. G-Protein-Coupled Receptors,Signal Fidelity, and Cell Transformation
48. Regulation of G proteins by Covalent Modification
49. Signaling Throught Gz
50. Mono-ADP-Ribosylation of Heterotrineric G Proteins
51. Specificity of G-Protein ?? Dimer Signaling
52. Reversible Palmitoylation in G Protein Signaling
53. The Influence of Intracellular Location on Funtion of Ras Proteins
54. Role of R-Ras in Cell Growth
55. The Ran GTPase: Celluar Roles and Regulation
56. Cdc42 and Its Cellular Funcions
57. Structure of Rho Family Targets

Index


   도서 상세설명   

Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.

Articles written and edited by experts in the field

Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses

Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

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